Compounds studied

The following groups of compounds and administration regimes have been studied in the past: 

• Opioids (fentanyl, remifentanyl, oxycodone, buprenorphine, alfentanyl, morphine, codeine, kappa-agonist) (epidural, spinal, iv, im, oral, transdermal)
• Opioid antagonists (i.v)
• Tramadol
• NSAID (COX1+2, COX2) (oral, transdermal)
• Acetaminophen (oral)
• NMDA-antagonister (oral, im, iv)
• Sodium ch. blockers (epidural, spinal, perineural, topical, iv, im)
• Antidepressants (oral) (velnafaxine, impiramine)
• Anticonvulsants (oral) (gabapentin, pregabalin)
• Alpha-2-agonists (epidural, iv)
• Tetrahydrocannabinol (im)
• Calcitonin (oral)
• Antispasmodic (oral)
• New classes !!!