Examples 2000-


Arendt-Nielsen L, Egsgaard LL, Petersen KK. Evidence for a central mode of action for etoricoxib (COX-2 Inhibitor) in patients with painful knee osteoarthritis. Pain. 2016 Mar 22. [Epub ahead of print]

Olesen, A. E., Sato, H., Nielsen, L. M., Staahl, C., Droney, J., Gretton, S., Branford, R., Drewes, A. M., Arendt-Nielsen, L., Riley, J., Ross, J. The Genetic Influences on Oxycodone Response Characteristics in Human Experimental Pain. Fundamental and Clinical Pharmacology, 2015;29(4):417-25.

Vuilleumier, P. H., Besson, M., Desmeules, J., Arendt-Nielsen, L., & Curatolo, M. Evaluation of anti-hyperalgesic and analgesic effects of two benzodiazepines in human experimental pain: a randomized placebo-controlled study. P L o S One, 2013; 8(3), Article No. 43896.

Olesen, A. E., Kristensen, K., Staahl, C., Kell, S., Wong, G. Y., Arendt-Nielsen, L., & Drewes, A. A population pharmacokinetic and pharmacodynamic study of a peripheral κ-opioid receptor agonist CR665 and oxycodone. Clinical Pharmacokinetics, 2013; 52(2), 125-137.

Gram M, Graversen C, Nielsen AK, Arendt-Nielsen T, Mørch CD, Andresen T, Drewes AM. A novel approach to pharmaco-EEG for investigating analgesics: assessment of spectral indices in single-sweep evoked brain potentials. Br J Clin Pharmacol. 2013; 76(6):951-63.

Arendt-Nielsen L, Andresen T, Malver LP, Oksche A, Mansikka H, Drewes AM. A double-blind, placebo-controlled study on the effect of buprenorphine and fentanyl on descending pain modulation: a human experimental study.Clin J Pain. 2012; 28(7):623-7.

Neziri, A. Y., Dickenmann, M., Scaramozzino, P., Andersen, O. K., Arendt-Nielsen, L., Dickenson, A. H., & Curatolo, M. Effect of intravenous tropisetron on modulation of pain and central hypersensitivity in chronic low back pain patients. Pain, 2012; 153(2), 311-318.

Andresen T, Staahl C, Oksche A, Mansikka H, Arendt-Nielsen L, Drewes AM. Effect of transdermal opioids in experimentally induced superficial, deep and hyperalgesic pain. Br J Pharmacol. 2011;164(3):934-45.

Andresen T, Upton RN, Foster DJ, Christrup LL, Arendt-Nielsen L, Drewes AM. Pharmacokinetic/pharmacodynamic relationships of transdermal buprenorphine and fentanyl in experimental human pain models. Basic Clin Pharmacol Toxicol. 2011;108(4):274-84.

Gerber, R. K. H., Nie, H., Arendt-Nielsen, L., Curatolo, M., & Graven-Nielsen, T. Local pain and spreading hyperalgesia induced by intramuscular injection of nerve growth factor are not reduced by local anesthesia of the muscle. Clinical Journal of Pain, 2011; 27(3), 240-247.

Olesen, A. E., Staahl, C., Arendt-Nielsen, L., & Drewes, A. M. Different effects of morphine and oxycodone in experimentally evoked hyperalgesia: a human translational study. British Journal of Clinical Pharmacology, 2010; 70(2), 189-200

Olesen, A. E., Upton, R., Foster, D. J. R., Staahl, C., Christrup, L. L., Arendt-Nielsen, L., & Drewes, A. M. A pharmacokinetic and pharmacodynamic study of oral oxycodone in a human experimental pain model of hyperalgesia. Clinical Pharmacokinetics, 2010; 49(12), 817-827

Arendt-Nielsen, L., Olesen, A. E., Staahl, C., Menzaghi, F., Kell, S., Wong, G. Y., & Drewes, A. M. Analgesic efficacy of peripheral Κappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model selective effect on visceral pain. Anesthesiology, 2009; 111(3), 616-624.

Eichenberger, U., Neff, F., Sveticic, G., Björgo, S., Petersen-Felix, S., Arendt-Nielsen, L., & Curatolo, M. Chronic phantom limb pain: the effects of calcitonin, ketamine, and their combination on pain and sensory thresholds. Anesthesia and Analgesia, 2008; 106(4), 1265-1273.

Naef, M., Curatolo, M., Petersen-Felix, S., Arendt-Nielsen, L., Zbinden, A., & Brenneisen, R. The analgesic effect of oral delta-9-tetrahydrocannabinol (THC), morphine, and a THC-morphine combination in healthy subjects under experimental pain conditions. Pain, 2003; 105(1-2), 79-88.

Luginbühl, M., Gerber, A., Schnider, T., Petersen-Felix, S., Arendt-Nielsen, L., & Curatolo, M. Modulation of remifentanil-induced analgesia, hyperalgesia, and tolerance by small-dose ketamine in humans. Anesthesia and Analgesia, 2003; 6(3), 726-732.

Eichenberger, U., Giani, C., Petersen-Felix, S., Graven-Nielsen, T., Arendt-Nielsen, L., & Curatolo, M. Lumbar epidural fentanyl: segmental spread and effect on temporal summation and muscle pain. British Journal of Anaesthesia, 2003; 90(4), 467-473.

Curatolo, M., Petersen-Felix, S., Gerber, A., & Arendt-Nielsen, L. Remifentanil inhibits muscular more than cutaneous pain in humans. British Journal of Anaesthesia, 2000; 85(4), 529-532.

Curatolo, M., Petersen-Felix, S., & Arendt-Nielsen, L. (2000). Sensory assessment of regional analgesia in humans: a review of methods and applications. Anesthesiology, 2000; 93(6), 1517-1530.

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